Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

As human lifespan increases, a greater fraction of the population is suffering from age-related cognitive impairments, making it important to elucidate a means to combat the effects of aging(1,2). Here we report that exposure of an aged animal to young blood can counteract and reverse pre-existing e...

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Publicado en:Nat Med
Main Authors: Villeda, Saul A, Plambeck, Kristopher E, Middeldorp, Jinte, Castellano, Joseph M, Mosher, Kira I, Luo, Jian, Smith, Lucas K, Bieri, Gregor, Lin, Karin, Berdnik, Daniela, Wabl, Rafael, Udeochu, Joe, Wheatley, Elizabeth G, Zou, Bende, Simmons, Danielle A, Xie, Xinmin S, Longo, Frank M, Wyss-Coray, Tony
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224436/
https://ncbi.nlm.nih.gov/pubmed/24793238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3569
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