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Novel Roles for P53 in the Genesis and Targeting of Tetraploid Cancer Cells

Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are believed to be precursors to whole chromosome aneuploidy. It is therefore important to determine how tetraploid cancer cells arise, and how to tar...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Davaadelger, Batzaya, Shen, Hong, Maki, Carl G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224386/
https://ncbi.nlm.nih.gov/pubmed/25380055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110844
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