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Novel Roles for P53 in the Genesis and Targeting of Tetraploid Cancer Cells

Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are believed to be precursors to whole chromosome aneuploidy. It is therefore important to determine how tetraploid cancer cells arise, and how to tar...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Davaadelger, Batzaya, Shen, Hong, Maki, Carl G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224386/
https://ncbi.nlm.nih.gov/pubmed/25380055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110844
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