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Dynamic Bayesian Testing of Sets of Variants in Complex Diseases

Rare genetic variants have recently been studied for genome-wide associations with human complex diseases. Existing rare variant methods are based on the hypothesis-testing framework that predefined variant sets need to be tested separately. The power of those methods is contingent upon accurate sel...

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Publicat a:Genetics
Autors principals: Zhang, Yu, Ghosh, Soumitra, Hakonarson, Hakon
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224176/
https://ncbi.nlm.nih.gov/pubmed/25217050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.167403
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