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Comparative evaluation of the new FDA approved THxID™-BRAF test with high resolution melting and sanger sequencing

BACKGROUND: Since patients diagnosed with BRAF V600E and V600K mutated advanced melanoma show response to treatment with MAP kinase inhibitors, several sensitive methods have been developed to determine the V600 allele status of melanoma patients. Vemurafenib (Zelboraf) and dabrafenib (Tafinlar) are...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Marchant, Julie, Mange, Alain, Larrieux, Marion, Costes, Valérie, Solassol, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223712/
https://ncbi.nlm.nih.gov/pubmed/25037456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-519
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