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Comparative evaluation of the new FDA approved THxID™-BRAF test with high resolution melting and sanger sequencing

BACKGROUND: Since patients diagnosed with BRAF V600E and V600K mutated advanced melanoma show response to treatment with MAP kinase inhibitors, several sensitive methods have been developed to determine the V600 allele status of melanoma patients. Vemurafenib (Zelboraf) and dabrafenib (Tafinlar) are...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Marchant, Julie, Mange, Alain, Larrieux, Marion, Costes, Valérie, Solassol, Jérôme
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223712/
https://ncbi.nlm.nih.gov/pubmed/25037456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-519
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