Chemical Conversion of Human Fibroblasts into Functional Schwann Cells

Direct transdifferentiation of somatic cells is a promising approach to obtain patient-specific cells for numerous applications. However, conversion across germ-layer borders often requires ectopic gene expression with unpredictable side effects. Here, we present a gene-free approach that allows eff...

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Pubblicato in:Stem Cell Reports
Autori principali: Thoma, Eva C., Merkl, Claudia, Heckel, Tobias, Haab, Rachel, Knoflach, Frederic, Nowaczyk, Corinne, Flint, Nicholas, Jagasia, Ravi, Jensen Zoffmann, Sannah, Truong, Hoa Hue, Petitjean, Pascal, Jessberger, Sebastian, Graf, Martin, Iacone, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223700/
https://ncbi.nlm.nih.gov/pubmed/25358782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.07.014
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