Chemical Conversion of Human Fibroblasts into Functional Schwann Cells

Direct transdifferentiation of somatic cells is a promising approach to obtain patient-specific cells for numerous applications. However, conversion across germ-layer borders often requires ectopic gene expression with unpredictable side effects. Here, we present a gene-free approach that allows eff...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Thoma, Eva C., Merkl, Claudia, Heckel, Tobias, Haab, Rachel, Knoflach, Frederic, Nowaczyk, Corinne, Flint, Nicholas, Jagasia, Ravi, Jensen Zoffmann, Sannah, Truong, Hoa Hue, Petitjean, Pascal, Jessberger, Sebastian, Graf, Martin, Iacone, Roberto
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223700/
https://ncbi.nlm.nih.gov/pubmed/25358782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.07.014
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