Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid Patients

Generation of functional spermatids from azoospermia patients is of unusual significance in the treatment of male infertility. Here, we report an efficient approach to obtain human functional spermatids from cryptorchid patients. Spermatogonia remained whereas meiotic germ cells were rare in cryptor...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Yang, Shi, Ping, Ping, Ma, Meng, Li, Peng, Tian, Ruhui, Yang, Hao, Liu, Yang, Gong, Yuehua, Zhang, Zhenzhen, Li, Zheng, He, Zuping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223697/
https://ncbi.nlm.nih.gov/pubmed/25358793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.004
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