Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid Patients

Generation of functional spermatids from azoospermia patients is of unusual significance in the treatment of male infertility. Here, we report an efficient approach to obtain human functional spermatids from cryptorchid patients. Spermatogonia remained whereas meiotic germ cells were rare in cryptor...

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Pubblicato in:Stem Cell Reports
Autori principali: Yang, Shi, Ping, Ping, Ma, Meng, Li, Peng, Tian, Ruhui, Yang, Hao, Liu, Yang, Gong, Yuehua, Zhang, Zhenzhen, Li, Zheng, He, Zuping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223697/
https://ncbi.nlm.nih.gov/pubmed/25358793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.004
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