A Novel Immuno-Competitive Capture Mass Spectrometry Strategy for Protein–Protein Interaction Profiling Reveals That LATS Kinases Regulate HCV Replication Through NS5A Phosphorylation*

Mapping protein–protein interactions is essential to fully characterize the biological function of a protein and improve our understanding of diseases. Affinity purification coupled to mass spectrometry (AP-MS) using selective antibodies against a target protein has been commonly applied to study pr...

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Detalles Bibliográficos
Publicado en:Mol Cell Proteomics
Main Authors: Meistermann, Hélène, Gao, Junjun, Golling, Sabrina, Lamerz, Jens, Le Pogam, Sophie, Tzouros, Manuel, Sankabathula, Sailaja, Gruenbaum, Lore, Nájera, Isabel, Langen, Hanno, Klumpp, Klaus, Augustin, Angélique
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223490/
https://ncbi.nlm.nih.gov/pubmed/25044019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.028977
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