The Selenium Metabolite Methylselenol Regulates the Expression of Ligands That Trigger Immune Activation through the Lymphocyte Receptor NKG2D

For decades, selenium research has been focused on the identification of active metabolites, which are crucial for selenium chemoprevention of cancer. In this context, the metabolite methylselenol (CH(3)SeH) is known for its action to selectively kill transformed cells through mechanisms that includ...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Hagemann-Jensen, Michael, Uhlenbrock, Franziska, Kehlet, Stephanie, Andresen, Lars, Gabel-Jensen, Charlotte, Ellgaard, Lars, Gammelgaard, Bente, Skov, Søren
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223354/
https://ncbi.nlm.nih.gov/pubmed/25258323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591537
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