NRF2/Long Noncoding RNA ROR Signaling Regulates Mammary Stem Cell Expansion and Protects against Estrogen Genotoxicity

Long noncoding RNAs (lncRNAs) have emerged as key regulators of gene expression in embryonic stem cell (ESC) self-renewal and differentiation. In ESCs, lncRNAs are regulated at the genetic level via transcription factor binding to lncRNA gene promoters. Here we demonstrate that the key cytoprotectiv...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Yongshu, Xia, Jixiang, Li, Qinglin, Yao, Yuan, Eades, Gabriel, Gernapudi, Ramkishore, Duru, Nadire, Kensler, Thomas W., Zhou, Qun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223331/
https://ncbi.nlm.nih.gov/pubmed/25231996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604868
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