NRF2/Long Noncoding RNA ROR Signaling Regulates Mammary Stem Cell Expansion and Protects against Estrogen Genotoxicity

Long noncoding RNAs (lncRNAs) have emerged as key regulators of gene expression in embryonic stem cell (ESC) self-renewal and differentiation. In ESCs, lncRNAs are regulated at the genetic level via transcription factor binding to lncRNA gene promoters. Here we demonstrate that the key cytoprotectiv...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Yongshu, Xia, Jixiang, Li, Qinglin, Yao, Yuan, Eades, Gabriel, Gernapudi, Ramkishore, Duru, Nadire, Kensler, Thomas W., Zhou, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223331/
https://ncbi.nlm.nih.gov/pubmed/25231996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604868
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