Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation

The human molecular chaperone protein DNAJB6 was recently found to inhibit the formation of amyloid fibrils from polyglutamine peptides associated with neurodegenerative disorders such as Huntington disease. We show in the present study that DNAJB6 also inhibits amyloid formation by an even more agg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Månsson, Cecilia, Arosio, Paolo, Hussein, Rasha, Kampinga, Harm H., Hashem, Reem M., Boelens, Wilbert C., Dobson, Christopher M., Knowles, Tuomas P. J., Linse, Sara, Emanuelsson, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223311/
https://ncbi.nlm.nih.gov/pubmed/25217638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595124
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados