Understanding Nucleotide-Regulated FtsZ Filament Dynamics and the Monomer Assembly Switch with Large-Scale Atomistic Simulations

Bacterial cytoskeletal protein FtsZ assembles in a head-to-tail manner, forming dynamic filaments that are essential for cell division. Here, we study their dynamics using unbiased atomistic molecular simulations from representative filament crystal structures. In agreement with experimental data, w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Ramírez-Aportela, Erney, López-Blanco, José Ramón, Andreu, José Manuel, Chacón, Pablo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2014
Pynciau:
Proteins and Nucleic Acids
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223170/
https://ncbi.nlm.nih.gov/pubmed/25418101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.09.033
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