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Understanding Nucleotide-Regulated FtsZ Filament Dynamics and the Monomer Assembly Switch with Large-Scale Atomistic Simulations

Bacterial cytoskeletal protein FtsZ assembles in a head-to-tail manner, forming dynamic filaments that are essential for cell division. Here, we study their dynamics using unbiased atomistic molecular simulations from representative filament crystal structures. In agreement with experimental data, w...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Ramírez-Aportela, Erney, López-Blanco, José Ramón, Andreu, José Manuel, Chacón, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223170/
https://ncbi.nlm.nih.gov/pubmed/25418101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.09.033
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