Understanding Nucleotide-Regulated FtsZ Filament Dynamics and the Monomer Assembly Switch with Large-Scale Atomistic Simulations

Bacterial cytoskeletal protein FtsZ assembles in a head-to-tail manner, forming dynamic filaments that are essential for cell division. Here, we study their dynamics using unbiased atomistic molecular simulations from representative filament crystal structures. In agreement with experimental data, w...

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Bibliographic Details
Published in:Biophys J
Main Authors: Ramírez-Aportela, Erney, López-Blanco, José Ramón, Andreu, José Manuel, Chacón, Pablo
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2014
Subjects:
Proteins and Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223170/
https://ncbi.nlm.nih.gov/pubmed/25418101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.09.033
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