Programmed Ribosomal Frameshift Alters Expression of West Nile Virus Genes and Facilitates Virus Replication in Birds and Mosquitoes

West Nile virus (WNV) is a human pathogen of significant medical importance with close to 40,000 cases of encephalitis and more than 1,600 deaths reported in the US alone since its first emergence in New York in 1999. Previous studies identified a motif in the beginning of non-structural gene NS2A o...

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Udgivet i:PLoS Pathog
Main Authors: Melian, Ezequiel Balmori, Hall-Mendelin, Sonja, Du, Fangyao, Owens, Nick, Bosco-Lauth, Angela M., Nagasaki, Tomoko, Rudd, Stephen, Brault, Aaron C., Bowen, Richard A., Hall, Roy A., van den Hurk, Andrew F., Khromykh, Alexander A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223154/
https://ncbi.nlm.nih.gov/pubmed/25375107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004447
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