Programmed Ribosomal Frameshift Alters Expression of West Nile Virus Genes and Facilitates Virus Replication in Birds and Mosquitoes

West Nile virus (WNV) is a human pathogen of significant medical importance with close to 40,000 cases of encephalitis and more than 1,600 deaths reported in the US alone since its first emergence in New York in 1999. Previous studies identified a motif in the beginning of non-structural gene NS2A o...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Melian, Ezequiel Balmori, Hall-Mendelin, Sonja, Du, Fangyao, Owens, Nick, Bosco-Lauth, Angela M., Nagasaki, Tomoko, Rudd, Stephen, Brault, Aaron C., Bowen, Richard A., Hall, Roy A., van den Hurk, Andrew F., Khromykh, Alexander A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223154/
https://ncbi.nlm.nih.gov/pubmed/25375107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004447
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