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The di-peptide Trp-His activates AMP-activated protein kinase and enhances glucose uptake independently of insulin in L6 myotubes

The di-peptide Trp-His (WH) has vasorelaxant and anti-atherosclerotic functions. We hypothesized that WH has multiple biological functions and may aid AMP-activated protein kinase (AMPK) activation and affect the glucose transport system in skeletal muscle. First, we examined whether WH or His-Trp (...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Soga, Minoru, Ohashi, Ayaka, Taniguchi, Megumi, Matsui, Toshiro, Tsuda, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223153/
https://ncbi.nlm.nih.gov/pubmed/25383313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.10.008
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