BMS309403 Stimulates Glucose Uptake in Myotubes through Activation of AMP-Activated Protein Kinase

BMS309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases. Here we discovered an off-target activity of BMS309403 in that it stimulates glucose uptake in C2C12 myotubes in...

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Detalhes bibliográficos
Main Authors: Lin, Wanhua, Huang, Xiaoli, Zhang, Lina, Chen, Dongmei, Wang, Dongye, Peng, Qilong, Xu, Lei, Li, Jingya, Liu, Xiujie, Li, Kuai, Ding, Ke, Jin, Shouguang, Li, Jia, Wu, Donghai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432117/
https://ncbi.nlm.nih.gov/pubmed/22952994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044570
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