ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for antifungal drug resistance and virulence. The latter phenotype is especially striking, as loss of SrbA results in complete...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chung, Dawoon, Barker, Bridget M., Carey, Charles C., Merriman, Brittney, Werner, Ernst R., Lechner, Beatrix E., Dhingra, Sourabh, Cheng, Chao, Xu, Wenjie, Blosser, Sara J., Morohashi, Kengo, Mazurie, Aurélien, Mitchell, Thomas K., Haas, Hubertus, Mitchell, Aaron P., Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223079/
https://ncbi.nlm.nih.gov/pubmed/25375670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004487
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