The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration

BACKGROUND: The actin-bundling protein Fascin (FSCN1) is a tumor marker that is highly expressed in numerous types of cancer including lymphomas and is important for migration and metastasis of tumor cells. Fascin has also been detected in B lymphocytes that are freshly-infected with Epstein-Barr vi...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Mohr, Caroline F, Kalmer, Martina, Gross, Christine, Mann, Melanie C, Sterz, Kai R, Kieser, Arnd, Fleckenstein, Bernhard, Kress, Andrea K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222691/
https://ncbi.nlm.nih.gov/pubmed/25105941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0046-x
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