Hybridizing Ultraviolet Photodissociation with Electron Transfer Dissociation for Intact Protein Characterization

[Image: see text] We report a hybrid fragmentation method involving electron transfer dissociation (ETD) combined with ultraviolet photodissociation (UVPD) at 193 nm for analysis of intact proteins in an Orbitrap mass spectrometer. Integrating the two fragmentation methods resulted in an increase in...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Cannon, Joe R., Holden, Dustin D., Brodbelt, Jennifer S.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222623/
https://ncbi.nlm.nih.gov/pubmed/25270663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac5036082
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