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Hybridizing Ultraviolet Photodissociation with Electron Transfer Dissociation for Intact Protein Characterization

[Image: see text] We report a hybrid fragmentation method involving electron transfer dissociation (ETD) combined with ultraviolet photodissociation (UVPD) at 193 nm for analysis of intact proteins in an Orbitrap mass spectrometer. Integrating the two fragmentation methods resulted in an increase in...

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Bibliografische gegevens
Gepubliceerd in:Anal Chem
Hoofdauteurs: Cannon, Joe R., Holden, Dustin D., Brodbelt, Jennifer S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222623/
https://ncbi.nlm.nih.gov/pubmed/25270663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac5036082
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