Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

BACKGROUND: Chimeric mice with humanized livers represent a promising tool for infections with Plasmodium falciparum to evaluate novel methods for prevention and treatment of pre-erythrocytic stages. Adequate assessment of hepatic infections is generally compromised by the limited number of human he...

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Bibliographic Details
Published in:Malar J
Main Authors: Foquet, Lander, Hermsen, Cornelus C, van Gemert, Geert-Jan, Libbrecht, Louis, Sauerwein, Robert, Meuleman, Philip, Leroux-Roels, Geert
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222492/
https://ncbi.nlm.nih.gov/pubmed/24267791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-430
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