The toxicity of very prolonged courses of PEGasparaginase or Erwinia asparaginase in relation to asparaginase activity, with a special focus on dyslipidemia

We prospectively studied the incidence and clinical course of hypertriglyceridemia and hypercholesterolemia during very prolonged use of asparaginase in relation to levels of asparaginase activity in children with acute lymphoblastic leukemia. We also evaluated the incidence of pancreatitis, thrombo...

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Publicado en:Haematologica
Autores principales: Tong, Wing H., Pieters, Rob, de Groot-Kruseman, Hester A., Hop, Wim C. J., Boos, Joachim, Tissing, Wim J. E., van der Sluis, Inge M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222477/
https://ncbi.nlm.nih.gov/pubmed/25150254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.109413
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