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Acute Psychosocial Stress-Mediated Changes in the Expression and Methylation of Perforin in Chronic Fatigue Syndrome

Perforin (PRF1) is essential for immune surveillance and studies report decreased perforin in chronic fatigue syndrome (CFS), an illness potentially associated with stress and/or infection. We hypothesize that stress can influence regulation of PRF1 expression, and that this regulation will differ b...

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Detalhes bibliográficos
Publicado no:Genet Epigenet
Main Authors: Falkenberg, Virginia R, Whistler, Toni, Murray, Janna R, Unger, Elizabeth R, Rajeevan, Mangalathu S
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222335/
https://ncbi.nlm.nih.gov/pubmed/25512702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GEG.S10944
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