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Determination of quantitative and site-specific DNA methylation of perforin by pyrosequencing
BACKGROUND: Differential expression of perforin (PRF1), a gene with a pivotal role in immune surveillance, can be attributed to differential methylation of CpG sites in its promoter region. A reproducible method for quantitative and CpG site-specific determination of perforin methylation is required...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704226/ https://ncbi.nlm.nih.gov/pubmed/19523225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-104 |
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