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Indoxyl sulfate promotes apoptosis in cultured osteoblast cells

BACKGROUND: Indoxyl sulfate (IS), an organic anion uremic toxin, promotes the progression of renal dysfunction. Some studies have suggested that IS inhibits osteoclast differentiation and suppresses parathyroid hormone (PTH)-stimulated intracellular cAMP production, decreases PTH receptor expression...

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Bibliographic Details
Published in:BMC Pharmacol Toxicol
Main Authors: Kim, Young-Hee, Kwak, Kyung-Ah, Gil, Hyo-Wook, Song, Ho-Yeon, Hong, Sae-Yong
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222141/
https://ncbi.nlm.nih.gov/pubmed/24289746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-60
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