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The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer

The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, speci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Tissue Eng
Hauptverfasser: Magdeldin, Tarig, López-Dávila, Víctor, Villemant, Cecile, Cameron, Grant, Drake, Rosemary, Cheema, Umber, Loizidou, Marilena
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221936/
https://ncbi.nlm.nih.gov/pubmed/25383169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2041731414544183
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