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The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer

The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, speci...

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Detalhes bibliográficos
Publicado no:J Tissue Eng
Main Authors: Magdeldin, Tarig, López-Dávila, Víctor, Villemant, Cecile, Cameron, Grant, Drake, Rosemary, Cheema, Umber, Loizidou, Marilena
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221936/
https://ncbi.nlm.nih.gov/pubmed/25383169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2041731414544183
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