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A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family

Autosomal dominant optic atrophy (ADOA) is the most frequent form of hereditary optic neuropathy and occurs due to the degeneration of the retinal ganglion cells. To identify the genetic defect in a family with putative ADOA, we performed capture next generation sequencing (CNGS) to screen known ret...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhang, Liping, Shi, Wei, Song, Liming, Zhang, Xiao, Cheng, Lulu, Wang, Yanfang, Ge, Xianglian, Li, Wei, Zhang, Wei, Min, Qingjie, Jin, Zi-Bing, Qu, Jia, Gu, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221781/
https://ncbi.nlm.nih.gov/pubmed/25374051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06936
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