Flattop regulates basal body docking and positioning in mono- and multiciliated cells

Planar cell polarity (PCP) regulates basal body (BB) docking and positioning during cilia formation, but the underlying mechanisms remain elusive. In this study, we investigate the uncharacterized gene Flattop (Fltp) that is transcriptionally activated during PCP acquisition in ciliated tissues. Flt...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Gegg, Moritz, Böttcher, Anika, Burtscher, Ingo, Hasenoeder, Stefan, Van Campenhout, Claude, Aichler, Michaela, Walch, Axel, Grant, Seth G N, Lickert, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221739/
https://ncbi.nlm.nih.gov/pubmed/25296022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03842
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