miR-98 suppresses melanoma metastasis through a negative feedback loop with its target gene IL-6

Dysregulated microRNA (miRNA) expression has a critical role in tumor development and metastasis. However, the mechanism by which miRNAs control melanoma metastasis is unknown. Here, we report reduced miR-98 expression in melanoma tissues with increasing tumor stage as well as metastasis; its expres...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Li, Fei, Li, Xin-ji, Qiao, Li, Shi, Fei, Liu, Wen, Li, You, Dang, Yu-ping, Gu, Wei-jie, Wang, Xiao-gang, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221693/
https://ncbi.nlm.nih.gov/pubmed/25277211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.63
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