Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

Leptin, a peptide hormone from adipose tissue and key player in weight regulation, has been suggested to be involved in sleep and cognition and to exert antidepressant-like effects, presumably via its action on the HPA-axis and hippocampal function. This led us to investigate whether genetic variant...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Eur Neuropsychopharmacol
Κύριοι συγγραφείς: Kloiber, Stefan, Ripke, Stephan, Kohli, Martin A., Reppermund, Simone, Salyakina, Daria, Uher, Rudolf, McGuffin, Peter, Perlis, Roy H., Hamilton, Steven P., Pütz, Benno, Hennings, Johannes, Brückl, Tanja, Klengel, Torsten, Bettecken, Thomas, Ising, Marcus, Uhr, Manfred, Dose, Tatjana, Unschuld, Paul G., Zihl, Josef, Binder, Elisabeth, Müller-Myhsok, Bertram, Holsboer, Florian, Lucae, Susanne
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221661/
https://ncbi.nlm.nih.gov/pubmed/23026132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2012.08.010
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