Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

Leptin, a peptide hormone from adipose tissue and key player in weight regulation, has been suggested to be involved in sleep and cognition and to exert antidepressant-like effects, presumably via its action on the HPA-axis and hippocampal function. This led us to investigate whether genetic variant...

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Detaylı Bibliyografya
Yayımlandı:Eur Neuropsychopharmacol
Asıl Yazarlar: Kloiber, Stefan, Ripke, Stephan, Kohli, Martin A., Reppermund, Simone, Salyakina, Daria, Uher, Rudolf, McGuffin, Peter, Perlis, Roy H., Hamilton, Steven P., Pütz, Benno, Hennings, Johannes, Brückl, Tanja, Klengel, Torsten, Bettecken, Thomas, Ising, Marcus, Uhr, Manfred, Dose, Tatjana, Unschuld, Paul G., Zihl, Josef, Binder, Elisabeth, Müller-Myhsok, Bertram, Holsboer, Florian, Lucae, Susanne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221661/
https://ncbi.nlm.nih.gov/pubmed/23026132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2012.08.010
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