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Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels
Leptin, a peptide hormone from adipose tissue and key player in weight regulation, has been suggested to be involved in sleep and cognition and to exert antidepressant-like effects, presumably via its action on the HPA-axis and hippocampal function. This led us to investigate whether genetic variant...
Zapisane w:
| Wydane w: | Eur Neuropsychopharmacol |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4221661/ https://ncbi.nlm.nih.gov/pubmed/23026132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2012.08.010 |
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