Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells

BACKGROUND: Huntington’s disease (HD) is a monogenic disorder caused by an aberrant expansion of CAG repeats in the huntingtin gene (HTT). Pathogenesis is associated with expression of the mutant (mHTT) protein in the CNS, with its levels most likely related to disease progression and symptom severi...

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Vydáno v:BMC Biochem
Hlavní autoři: Massai, Luisa, Petricca, Lara, Magnoni, Letizia, Rovetini, Luca, Haider, Salman, Andre, Ralph, Tabrizi, Sarah J, Süssmuth, Sigurd D, Landwehrmeyer, Bernhard G, Caricasole, Andrea, Pollio, Giuseppe, Bernocco, Simonetta
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221641/
https://ncbi.nlm.nih.gov/pubmed/24274906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-14-34
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