[Pt(O,O’-acac)(γ-acac)(DMS)] Alters SH-SY5Y Cell Migration and Invasion by the Inhibition of Na(+)/H(+) Exchanger Isoform 1 Occurring through a PKC-ε/ERK/mTOR Pathway

We previously showed that [Pt(O,O’-acac)(γ-acac)(DMS)] ([Pt(acac)(2)(DMS)]) exerted substantial cytotoxic effects in SH-SY5Y neuroblastoma cells, and decreased metalloproteases (MMPs) production and cells migration in MCF-7 breast cancer cells. The ubiquitously distributed sodium-hydrogen antiporter...

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Vydáno v:PLoS One
Hlavní autoři: Muscella, Antonella, Vetrugno, Carla, Calabriso, Nadia, Cossa, Luca Giulio, De Pascali, Sandra Angelica, Fanizzi, Francesco Paolo, Marsigliante, Santo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221608/
https://ncbi.nlm.nih.gov/pubmed/25372487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112186
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