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Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a specific three-dimensional structure and are thus...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Sun, Hongguang, Zhu, Xun, Lu, Patrick Y, Rosato, Roberto R, Tan, Wen, Zu, Youli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221593/
https://ncbi.nlm.nih.gov/pubmed/25093706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.32
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