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Alterations in connexin 43 during diabetic cardiomyopathy: competition of tyrosine nitration versus phosphorylation

OBJECTIVE: Cardiac conduction abnormalities are observed early in the progression of Type I diabetes, but the mechanism(s) involved are undefined. Connexin 43, a critical component of ventricular gap junctions, depends on tyrosine phosphorylation status to modulate channel conductance - alterations...

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Detalhes bibliográficos
Publicado no:J Diabetes
Main Authors: JOSHI, Mandar S., MIHM, Michael J., COOK, Angela C., SCHANBACHER, Brandon L., BAUER, John Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221578/
https://ncbi.nlm.nih.gov/pubmed/24796789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1753-0407.12164
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