Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.

Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system that serves as a model for the human disease multiple sclerosis. We evaluated rolipram, a type IV phosphodiesterase inhibitor, for its efficacy in preventing EAE in the common marmoset Callithrix jac...

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Huvudupphovsmän: Genain, C P, Roberts, T, Davis, R L, Nguyen, M H, Uccelli, A, Faulds, D, Li, Y, Hedgpeth, J, Hauser, S L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC42215/
https://ncbi.nlm.nih.gov/pubmed/7536938
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