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Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system that serves as a model for the human disease multiple sclerosis. We evaluated rolipram, a type IV phosphodiesterase inhibitor, for its efficacy in preventing EAE in the common marmoset Callithrix jac...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1995
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC42215/ https://ncbi.nlm.nih.gov/pubmed/7536938 |
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