Bisphosphonates Inhibit Stellate Cell Activity and Enhance Antitumor Effects of Nanoparticle Albumin Bound-Paclitaxel in Pancreatic Ductal Adenocarcinoma

Pancreatic stellate cells (PSCs) have been recognized as the principal cells responsible for the production of fibrosis in PDAC. Recently PSCs have been noted to share characteristics with cells of monocyte-macrophage lineage (MML cells). Thus, we tested whether PSCs could be targeted with the nitro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Cancer Ther
Autores principales: Gonzalez-Villasana, Vianey, Rodriguez-Aguayo, Cristian, Arumugam, Thiruvengadam, Cruz-Monserrate, Zobeida, Fuentes-Mattei, Enrique, Deng, Defeng, Hwang, Rosa F., Wang, Huamin, Ivan, Cristina, Garza, Raul Joshua, Cohen, Evan, Gao, Hui, Armaiz-Pena, Guillermo N., Monroig-Bosque, Paloma del C., Philip, Bincy, Rashed, Mohammed H., Aslan, Burcu, Erdogan, Mumin Alper, Gutierrez-Puente, Yolanda, Ozpolat, Bulent, Reuben, James M., Sood, Anil K., Logsdon, Craig, Lopez-Berestein, Gabriel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221441/
https://ncbi.nlm.nih.gov/pubmed/25193509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0028
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares