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A Pilot Study of Estradiol Followed by Exemestane for Reversing Endocrine Resistance in Postmenopausal Women With Hormone Receptor-Positive Metastatic Breast Cancer

BACKGROUND. Endocrine resistance is a frequent complication, and strategies to reverse it are a high research priority for metastatic breast cancer (MBC) that is hormone receptor positive. Preclinical data suggest re-exposure to estrogen induces tumor regression in tamoxifen-resistant tumors. We con...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Chalasani, Pavani, Stopeck, Alison, Clarke, Kathryn, Livingston, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221379/
https://ncbi.nlm.nih.gov/pubmed/25260365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0306
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