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A phase I clinical trial of bavituximab and paclitaxel in patients with HER2 negative metastatic breast cancer
Bavituximab is a chimeric monoclonal antibody that targets phosphatidylserine (PS). PS is externalized on cells in the tumor microenvironment when exposed to hypoxia and/or other physiological stressors. On attaching to PS, bavituximab is thought to promote antitumor immunity through its effects on...
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| Publicado no: | Cancer Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529343/ https://ncbi.nlm.nih.gov/pubmed/25826750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.447 |
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