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3-amino-4-(3-hexylphenylamino)-4-oxobutyl phosphonic acid (W146), a Selective Antagonist of Sphingosine-1-phospahte Receptor Subtype 1, Enhances AMD3100-stimulated Mobilization of Hematopoietic Stem Progenitor Cells in Animals
Sphingosine-1-phosphate (S1P), a serum-borne bioactive lipid, regulates various physiological functions. We observed that the S1P receptor subtype 1 (S1P(1)), a high affinity G-protein coupled receptor of S1P, is the major S1P receptor expressed in the Kit(+)/Sca-1(+)/Lin(−) (KSL) hematopoietic stem...
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| Publicado no: | J Biochem Pharmacol Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4221244/ https://ncbi.nlm.nih.gov/pubmed/25383272 |
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