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3-amino-4-(3-hexylphenylamino)-4-oxobutyl phosphonic acid (W146), a Selective Antagonist of Sphingosine-1-phospahte Receptor Subtype 1, Enhances AMD3100-stimulated Mobilization of Hematopoietic Stem Progenitor Cells in Animals

Sphingosine-1-phosphate (S1P), a serum-borne bioactive lipid, regulates various physiological functions. We observed that the S1P receptor subtype 1 (S1P(1)), a high affinity G-protein coupled receptor of S1P, is the major S1P receptor expressed in the Kit(+)/Sca-1(+)/Lin(−) (KSL) hematopoietic stem...

詳細記述

保存先:
書誌詳細
出版年:J Biochem Pharmacol Res
主要な著者: Liu, Jingjing, Zhao, Jiawei, Lee, Jen-Fu, Gartung, Allison, Jawadi, Hiba, Zhang, Wenliang, Lominadze, David, Lee, Menq-Jer
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221244/
https://ncbi.nlm.nih.gov/pubmed/25383272
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