Computational and Functional Characterization of Angiogenin Mutations, and Correlation with Amyotrophic Lateral Sclerosis

The Angiogenin (ANG) gene is frequently mutated in patients suffering from the neurodegenerative disease - amyotrophic lateral sclerosis (ALS). Most of the ALS-causing mutations in Angiogenin affect either its ribonucleolytic or nuclear translocation activity. Here we report the functional character...

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Bibliographic Details
Published in:PLoS One
Main Authors: Padhi, Aditya K., Banerjee, Kamalika, Gomes, James, Banerjee, Manidipa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221194/
https://ncbi.nlm.nih.gov/pubmed/25372031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111963
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