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Group A streptococcal pyrogenic exotoxin: pyrogenicity, alteration of blood-brain barrier, and separation of sites for pyrogenicity and enhancement of lethal endotoxin shock.

Group A streptococcal pyrogenic exotoxin type C (SPE C) was shown to produce fever by crossing the blood-brain barrier. The toxin directly stimulated the hypothalamic fever response control center, thus bypassing a requirement for endogenous pyrogen release. SPE C was detected in the cerebrospinal f...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Schlievert, P M, Watson, D W
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1978
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC422062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/361577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.21.3.753-763.1978
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